ALPP Antibody (N-term)

Synthetic Peptide

There are at least four distinct but related alkaline
phosphatases: intestinal, placental, placental-like, and
liver/bone/kidney (tissue non-specific). The first three are
located together on chromosome 2 while the tissue non-specific form
is located on chromosome 1. The product of this gene is a membrane
bound glycosylated enzyme, also referred to as the heat stable
form, that is expressed primarily in the placenta although it is
closely related to the intestinal form of the enzyme as well as to
the placental-like form. The coding sequence for this form of
alkaline phosphatase is unique in that the 3' untranslated region
contains multiple copies of an Alu family repeat. In addition, this
gene is polymorphic and three common alleles (type 1, type 2 and
type 3) for this form of alkaline phosphatase have been well
characterized.

Polyclonal

250

Affinity Purified Rabbit Polyclonal Antibody (Pab)

ALPP Antibody (N-term) (Cat. #AP14937a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ALPP antibody detected the ALPP protein (arrow).

1:1000

WB

ALPP Antibody (N-term) (AP14937a)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ALPP Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

1:10~50

Rabbit Ig

56-83

This ALPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human ALPP.