KCND2 Antibody (N-term)

Synthetic Peptide

Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. Four sequence-related
potassium channel genes - shaker, shaw, shab, and shal - have been
identified in Drosophila, and each has been shown to have human
homolog(s). This gene encodes a member of the potassium channel,
voltage-gated, shal-related subfamily, members of which form
voltage-activated A-type potassium ion channels and are prominent
in the repolarization phase of the action potential. This member
mediates a rapidly inactivating, A-type outward potassium current
which is not under the control of the N terminus as it is in Shaker
channels.

Polyclonal

3751

Affinity Purified Rabbit Polyclonal Antibody (Pab)

KCND2 Antibody (N-term) (Cat. #AP14832a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KCND2 antibody detected the KCND2 protein (arrow).

1:1000

IHC-P

Q63881; P59995; Q9Z0V2; NP_036413.1

Rabbit Ig

123-151

This KCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the N-terminal region of human KCND2.