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CD70 Antibody (Center)

CD70 Antibody (Center)

Item no.	ABC-AP14744c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Carcinoma Hematology Lymphoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7
Available
Primary Accession	P32970
Other Accession	NP_001243.1
Antigen Type	Synthetic Peptide
Bio Background	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Bio References	Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010) Shaw, J., et al. Blood 115(15):3051-3057(2010) Yu, S.E., et al. Mol. Cells 29(2):217-221(2010) Kozlowska, A., et al. J. Rheumatol. 37(1):53-59(2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Gene ID	970
Gene Name	CD70
Reactivity	H
Calculated MW	21118
Antigen Region	72-101
Antigen Source	HUMAN
Target/Specificity	This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
NCBI Accession	NP_001243.1

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Amount: 80 ul

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