Item no. |
ABC-AP14504b-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PHLDA2, BWR1C, HLDA2, IPL, TSSC3, Pleckstrin homology-like domain family A member 2, Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein, Imprinted in placenta and liver protein, Tumor-suppressing STF cDNA 3 protein, p17-Beckwith-Wiedemann region 1 C, p17-BWR1C, Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein |
Available |
|
Primary Accession |
Q53GA4 |
Antigen Type |
Synthetic Peptide |
Application |
WB, IHC-P |
Bio Background |
This gene is located in a cluster of imprinted genes onchromosome 11p15.5, which is considered to be an important tumorsuppressor gene region. Alterations in this region may beassociated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, andbreast cancer. This gene has been shown to be imprinted, withpreferential expression from the maternal allele in placenta andliver. |
Bio References |
O'Seaghdha, C.M., et al. Hum. Mol. Genet. 19(21):4296-4303(2010)Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34(5):840-852(2010)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Tang, K.F., et al. Biochim. Biophys. Acta 1770(5):820-825(2007)Bertheau, P., et al. PLoS Med. 4 (3), E90 (2007) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB34223 |
Gene ID |
7262 |
Gene Name |
PHLDA2 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
PHLDA2 Antibody (C-term) (Cat. #AP14504b) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PHLDA2 antibody detected the PHLDA2 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
PHLDA2 Antibody (C-term) (AP14504b)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHLDA2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
NP_003302.1 |
Isotype |
Rabbit Ig |
Calculated MW |
17092 |
Antigen Region |
90-119 |
Antigen Source |
HUMAN |
Target/Specificity |
This PHLDA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human PHLDA2. |
NCBI Accession |
NP_003302.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.