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GRIK2 Antibody (C-term)

GRIK2 Antibody (C-term)

Item no.	ABC-AP14429B-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Glutamate receptor ionotropic, kainate 2, GluK2, Excitatory amino acid receptor 4, EAA4, Glutamate receptor 6, GluR-6, GluR6, GRIK2, GLUR6
Available
Primary Accession	Q13002
Other Accession	Q91755; P42260; P39087; Q38PU3; NP_786944.1; NP_068775.1; NP_001159719.1
Antigen Type	Synthetic Peptide
Bio Background	Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.
Bio References	Han, Y., et al. Biochemistry 49(43):9207-9216(2010) Holt, R., et al. Eur. J. Hum. Genet. 18(9):1013-1019(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Sampaio, A.S., et al. CNS Neurosci Ther (2010) In press : Sander, T., et al. Neurology 45(9):1713-1720(1995)
Gene ID	2898
Gene Name	GRIK2
Reactivity	H
Predicted	Pr, M, Rat, X
Calculated MW	102583
Antigen Region	828-856
Antigen Source	HUMAN
Target/Specificity	This GRIK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-856 amino acids from the C-terminal region of human GRIK2.
NCBI Accession	NP_001159719.1; NP_068775.1; NP_786944.1

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Amount: 80 ul

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