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GFRA2 Antibody (C-term)

GFRA2 Antibody (C-term)

Item no.	ABC-AP14374b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Carcinoma Sarcoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2, GFRA2, GDNFRB, RETL2, TRNR2
Available
Primary Accession	O00451
Other Accession	O08842; NP_001486.4; NP_001158510.1; NP_001158511.1
Antigen Type	Synthetic Peptide
Bio Background	Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
Bio References	Souza, R.P., et al. J Psychiatr Res 44(11):700-706(2010) Souza, R.P., et al. Psychopharmacology (Berl.) 210(3):347-354(2010) Buysschaert, I.D., et al. Allergy 65(5):616-622(2010) Lavedan, C., et al. Mol. Psychiatry 14(8):804-819(2009) Volpi, S., et al. J Clin Psychiatry 70(6):801-809(2009)
Gene ID	2675
Gene Name	GFRA2
Reactivity	H
Predicted	M
Calculated MW	51544
Antigen Region	361-390
Antigen Source	HUMAN
Target/Specificity	This GFRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human GFRA2.
NCBI Accession	NP_001158510.1; NP_001158511.1; NP_001486.4

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Amount: 80 ul

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