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TMC6 Antibody (N-term)

TMC6 Antibody (N-term)

Item no.	ABC-AP14212a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	EVER1, TMC6, EVIN1, Transmembrane channel-like protein 6, Epidermodysplasia verruciformis protein 1, Protein LAK-4
Available
Primary Accession	Q7Z403
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.
Bio References	McDermott, D.F., et al. Pediatr Dermatol 26(3):306-310(2009) Lazarczyk, M., et al. J. Exp. Med. 205(1):35-42(2008) Zuo, Y.G., et al. J. Dermatol. Sci. 44(3):153-159(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006) Donfack, J., et al. Int. J. Pediatr. Otorhinolaryngol. 70(7):1235-1240(2006)
Clonality	Polyclonal
Clone/Animal Names	RB34148
Gene ID	11322
Gene Name	TMC6
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	TMC6 Antibody (N-term) (Cat. #AP14212a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the TMC6 antibody detected the TMC6 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_009198.4; NP_001120670.1
Isotype	Rabbit Ig
Calculated MW	90045
Antigen Region	160-188
Antigen Source	HUMAN
Target/Specificity	This TMC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the N-terminal region of human TMC6.
NCBI Accession	NP_001120670.1; NP_009198.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 11/8/2024

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