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CRTC2 Antibody (C-term)

CRTC2 Antibody (C-term)

Item no.	ABC-AP14167b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Molecular Targets for Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies Brain Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2, CRTC2, TORC2
Available
Primary Accession	Q53ET0
Other Accession	NP_859066.1
Antigen Type	Synthetic Peptide
Bio Background	Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Bio References	Nakatsu, Y., et al. J. Biol. Chem. 285(43):33018-33027(2010) Kaizuka, T., et al. J. Biol. Chem. 285(26):20109-20116(2010) Lyo, D., et al. Biochem. Biophys. Res. Commun. 396(2):562-565(2010) Lu, M., et al. J. Am. Soc. Nephrol. 21(5):811-818(2010) Roulin, D., et al. Mol. Cancer 9, 57 (2010) :
Gene ID	200186
Gene Name	CRTC2
Reactivity	H
Calculated MW	73302
Antigen Region	664-693
Antigen Source	HUMAN
Target/Specificity	This CRTC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 664-693 amino acids from the C-terminal region of human CRTC2.
NCBI Accession	NP_859066.1

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Amount: 80 ul

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