Item no. |
ABC-AP13945b |
Manufacturer |
Abcepta
|
Amount |
400 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
TRAF3, CAP1, CRAF1, TNF receptor-associated factor 3, CAP-1, CD40 receptor-associated factor 1, CD40-binding protein, LMP1-associated protein 1, LAP1, 632-, CD40BP |
Available |
|
Primary Accession |
Q13114 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
The protein encoded by this gene is a member of the TNFreceptor associated factor (TRAF) protein family. TRAF proteinsassociate with, and mediate the signal transduction from, membersof the TNF receptor (TNFR) superfamily. This protein participatesin the signal transduction of CD40, a TNFR family member importantfor the activation of the immune response. This protein is found tobe a critical component of the lymphotoxin-beta receptor (LTbetaR)signaling complex, which induces NF-kappaB activation and celldeath initiated by LTbeta ligation. Epstein-Barr virus encodedlatent infection membrane protein-1 (LMP1) can interact with thisand several other members of the TRAF family, which may beessential for the oncogenic effects of LMP1. Three alternativelyspliced transcript variants encoding two distinct isoforms havebeen reported. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Song, Y.J., et al. Virus Genes 41(2):174-180(2010)Perez de Diego, R., et al. Immunity 33(3):400-411(2010)del Rio-Espinola, A., et al. Pharmacogenomics 11(6):763-772(2010)Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB22535 |
Gene ID |
7187 |
Gene Name |
TRAF3 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
TRAF3 Antibody (C-term) (Cat. #AP13945b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TRAF3 antibody detected the TRAF3 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
TRAF3 Antibody (C-term) (Cat. #AP13945b) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the TRAF3 antibody detected the TRAF3 protein (arrow). |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Other Accession |
Q60803; NP_663777.1; NP_663778.1; NP_003291.2 |
Isotype |
Rabbit Ig |
Calculated MW |
64490 |
Antigen Region |
490-517 |
Antigen Source |
HUMAN |
Target/Specificity |
This TRAF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-517 amino acids from the C-terminal region of human TRAF3. |
NCBI Accession |
NP_001186356.1; NP_003291.2; NP_663777.1; NP_663778.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.