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NR0B1 Antibody (Center)

NR0B1 Antibody (Center)

Item no.	ABC-AP13774c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, NR0B1, AHC, DAX1
Available
Primary Accession	P51843
Other Accession	NP_000466.2
Antigen Type	Synthetic Peptide
Bio Background	This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
Bio References	Li, N., et al. J. Clin. Endocrinol. Metab. 95 (9), E104-E111 (2010) : Nedumaran, B., et al. J. Biol. Chem. 285(12):9221-9232(2010) Kinsey, M., et al. Cancer Res. 69(23):9047-9055(2009) Nagl, F., et al. Am. J. Physiol., Cell Physiol. 297 (5), C1146-C1156 (2009) : Skinningsrud, B., et al. J. Clin. Endocrinol. Metab. 94(10):4086-4093(2009)
Gene ID	190
Gene Name	NR0B1
Reactivity	H
Calculated MW	51718
Antigen Region	304-333
Antigen Source	HUMAN
Target/Specificity	This NR0B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human NR0B1.
NCBI Accession	NP_000466.2

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Amount: 80 ul

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