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TARDBP Antibody (N-term)

TARDBP Antibody (N-term)

Item no.	ABC-AP13763a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Protein Aggregation, Clearance & Misfolding Neural Development Antibodies Blastoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	Immunofluorescence, Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43
Available
Primary Accession	Q13148
Other Accession	Q921F2; Q5ZLN5; NP_031401.1
Antigen Type	Synthetic Peptide
Bio Background	HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq].
Bio References	Kim, S.H., et al. J. Biol. Chem. 285(44):34097-34105(2010) Geser, F., et al. Arch. Neurol. 67(10):1238-1250(2010) Mackenzie, I.R., et al. Lancet Neurol 9(10):995-1007(2010) Shan, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16325-16330(2010) McKee, A.C., et al. J. Neuropathol. Exp. Neurol. 69(9):918-929(2010)
Gene ID	23435
Gene Name	TARDBP
Reactivity	H, M, Rat
Predicted	C
Calculated MW	44740
Antigen Region	1-30
Antigen Source	HUMAN
Target/Specificity	This TARDBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TARDBP.
NCBI Accession	NP_031401.1

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Amount: 80 ul

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