IL13 Antibody (C-term)

Synthetic Peptide

This gene encodes an immunoregulatory cytokine produced
primarily by activated Th2 cells. This cytokine is involved in
several stages of B-cell maturation and differentiation. It
up-regulates CD23 and MHC class II expression, and promotes IgE
isotype switching of B cells. This cytokine down-regulates
macrophage activity, thereby inhibits the production of
pro-inflammatory cytokines and chemokines. This cytokine is found
to be critical to the pathogenesis of allergen-induced asthma but
operates through mechanisms independent of IgE and eosinophils.
This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on
chromosome 5q, with this gene particularly close to IL4. [provided
by RefSeq].

Polyclonal

3596

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Confocal immunofluorescent analysis of IL13 Antibody (C-term) (Cat#AP13737b) with NCI-H460 cell line followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

1:10~50

WB

IL13 Antibody (C-term) (AP13737b)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL13 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

1:10~50

Rabbit Ig

118-146

This IL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the C-terminal region of human IL13.