Item no. |
ABC-AP1351d-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
APOBEC3G, DNA dC->dU-editing enzyme APOBEC-3G, APOBEC-related cytidine deaminase, APOBEC-related protein 9, CEM-15, Deoxycytidine deaminase, CEM15, ARCD, ARP-9, APOBEC-related protein, A3G, 354- |
Available |
|
Primary Accession |
Q9HC16 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
CEM15 is a member of the cytidine deaminase family. It is the product of one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. CEM15 has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. |
Bio References |
Kao, S., et al., J. Virol. 77(21):11398-11407 (2003).Stopak, K., et al., Mol. Cell 12(3):591-601 (2003).Mangeat, B., et al., Nature 424(6944):99-103 (2003).Zhang, H., et al., Nature 424(6944):94-98 (2003).Wedekind, J.E., et al., Trends Genet. 19(4):207-216 (2003). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB01788 |
Gene ID |
60489 |
Gene Name |
APOBEC3G |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
The anti-CEM15 Pab (Cat. #AP1351d) is used in Western blot to detect CEM15 in A375 cell lysate. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:50~100 |
Isotype |
Rabbit Ig |
Calculated MW |
46408 |
Antigen Region |
352-384 |
Antigen Source |
HUMAN |
Target/Specificity |
This APOBEC3G (CEM15) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-384 amino acids from the C-terminal region of human APOBEC3G (CEM15). |
NCBI Accession |
NP_068594.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.