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RNF8 Antibody (C-term)

RNF8 Antibody (C-term)

Manufacturer	Abcepta
Category	Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Specific against	other
Isotype	Ig
Applications	Western Blot
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP13431b-ev-80ul
Targets	UBE2K
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	E3 ubiquitin-protein ligase RNF8, hRNF8, 632-, RING finger protein 8, RNF8, KIAA0646
Primary Accession	O76064
Other Accession	NP_003949.1; NP_898901.1
Antigen Type	Synthetic Peptide
Bio Background	The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Bio References	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Koike, A., et al. Cancer Res. 70(17):6746-6756(2010) Lilley, C.E., et al. EMBO J. 29(5):943-955(2010) Noon, A.T., et al. Nat. Cell Biol. 12(2):177-184(2010) Ramachandran, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(2):809-814(2010)
Gene ID	9025
Gene Name	RNF8 {ECO:0000255\|HAMAP-Rule:MF_03067}
Reactivity	H, M
Calculated MW	55518
Antigen Region	335-364
Antigen Source	HUMAN
Target/Specificity	This RNF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-364 amino acids from the C-terminal region of human RNF8.
NCBI Accession	NP_003949.1; NP_898901.1

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Amount: 80 ul

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