Item no. |
ABC-AP13325c |
Manufacturer |
Abcepta
|
Amount |
400 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
SGEF, ARHGEF26, Rho guanine nucleotide exchange factor 26, SH3 domain-containing guanine exchange factor |
Available |
|
Primary Accession |
Q96DR7 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry. |
Bio References |
Yamada, S., et al. Oncogene 23(35):5901-5911(2004)Ellerbroek, S.M., et al. Mol. Biol. Cell 15(7):3309-3319(2004)Qi, H., et al. Endocrinology 144(5):1742-1752(2003) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB33350 |
Gene ID |
26084 |
Gene Name |
ARHGEF26 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
SGEF Antibody (Center) (Cat. #AP13325c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SGEF antibody detected the SGEF protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
SGEF Antibody (Center) (Cat. #AP13325c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SGEF Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
NP_056410.3 |
Isotype |
Rabbit Ig |
Calculated MW |
97346 |
Antigen Region |
378-406 |
Antigen Source |
HUMAN |
Target/Specificity |
This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF. |
NCBI Accession |
NP_001238891.1; NP_001238892.1; NP_056410.3 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.