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BAX Antibody (N-term)

BAX Antibody (N-term)

Item no.	ABC-AP13211a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Western Blot Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies Colorectal Cancer Testicular & Prostate Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4
Available
Primary Accession	Q07812
Other Accession	NP_004315.1; NP_620118.1; NP_620119.2; NP_620116.1
Antigen Type	Synthetic Peptide
Bio Background	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Bio References	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Montessuit, S., et al. Cell 142(6):889-901(2010) Ding, J., et al. J. Biol. Chem. 285(37):28749-28763(2010) Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press : Yu, D.K., et al. Zhonghua Zhong Liu Za Zhi 32(5):324-327(2010)
Gene ID	581
Gene Name	BAX
Reactivity	H
Calculated MW	21184
Antigen Region	28-56
Antigen Source	HUMAN
Target/Specificity	This BAX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human BAX.
NCBI Accession	NP_004315.1; NP_620116.1; NP_620118.1; NP_620119.2

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Amount: 80 ul

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