Manufacturer |
Abcepta
|
Category |
|
Type |
Antibody Primary |
Specific against |
other |
Isotype |
Ig |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, IHC-P |
Amount |
400 ul |
Host |
Rabbit |
Item no. |
ABC-AP12465b |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Primary Accession |
Q86Z02 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
The protein encoded by this gene belongs to the Ser/Thrfamily of protein kinases and HIPK subfamily. It phosphorylateshomeodomain transcription factors and may also function as aco-repressor for homeodomain transcription factors. Alternativesplicing results in four transcript variants encoding four distinctisoforms. |
Bio References |
Matre, V., et al. Biochem. Biophys. Res. Commun. 388(1):150-154(2009)Li, X., et al. J. Biol. Chem. 280(15):15061-15070(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)Song, J.J., et al. J. Biol. Chem. 278(47):47245-47252(2003) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB09623 |
Gene ID |
204851 |
Gene Name |
HIPK1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of HIPK1 Antibody (C-term) Pab (Cat. #AP12465b) pre-incubated without(lane 1) and with(lane 2) blocking peptide in MCF-7 cell line lysate. HIPK1 Antibody (C-term) (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
HIPK1 Antibody (C-term) (Cat. #AP12465b)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HIPK1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
O88904; NP_938009.1; NP_938010.1 |
Predicted |
M |
Isotype |
Rabbit Ig |
Calculated MW |
130843 |
Antigen Region |
893-922 |
Antigen Source |
HUMAN |
Target/Specificity |
This HIPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 893-922 amino acids from the C-terminal region of human HIPK1. |
NCBI Accession |
NP_689909.2; NP_852003.1; NP_938009.1; NP_938010.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.