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PITRM1 Antibody (Center)

PITRM1 Antibody (Center)

Item no.	ABC-AP12390c-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MP1, mitochondrial, PITRM1, KIAA1104, Presequence protease, Pitrilysin metalloproteinase 1, hMP1, Metalloprotease 1, 3424-, hPreP
Available
Primary Accession	Q5JRX3
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Bio References	Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Pinho, C.M., et al. Neurosci. Lett. 469(2):204-208(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009) Chow, K.M., et al. Biochemistry 48(13):2868-2877(2009)
Clonality	Polyclonal
Clone/Animal Names	RB31351
Gene ID	10531
Gene Name	PITRM1 (HGNC:17663)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	PITRM1 Antibody (Center) (Cat. #AP12390c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PITRM1 antibody detected the PITRM1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_055704.2
Isotype	Rabbit Ig
Calculated MW	117413
Antigen Region	490-518
Antigen Source	HUMAN
Target/Specificity	This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.
NCBI Accession	NP_001229236.1; NP_001229238.1; NP_055704.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 11/8/2024

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