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CYP5A1 Antibody (Center)

CYP5A1 Antibody (Center)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP12077c-ev
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	P24557
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Bio References	Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Wang, L.H., et al. Prostaglandins Other Lipid Mediat. 68-69, 409-422 (2002) : Tazawa, R., et al. Arch. Biochem. Biophys. 334(2):349-356(1996) Baek, S.J., et al. Gene 173(2):251-256(1996) Wang, L.H., et al. Arch. Biochem. Biophys. 315(2):273-278(1994)
Clonality	Polyclonal
Clone/Animal Names	RB17080
Gene ID	6916
Gene Name	TBXAS1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Legend image 1	CYP5A1 Antibody (Center) (Cat. #AP12077c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CYP5A1 antibody detected the CYP5A1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	CYP5A1 Antibody (Center) (Cat. #AP12077c)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP5A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q2PG45; Q2KIG5; NP_001052.2; NP_001124438.1
Predicted	B, Pr
Isotype	Rabbit Ig
Calculated MW	60518
Antigen Region	226-257
Antigen Source	HUMAN
Target/Specificity	This CYP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-257 amino acids from the Central region of human CYP5A1.
NCBI Accession	NP_001052.2; NP_001124438.1; NP_001159726.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 8/2/2024