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JMJD2B Antibody (N-term)

JMJD2B Antibody (N-term)

Item no.	ABC-AP11950a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Carcinoma Hematology Leukemia Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Clone	1761CT158.12.76
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Lysine-specific demethylase 4B, 11411-, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KDM4B, JHDM3B, JMJD2B, KIAA0876
Available
Primary Accession	O94953
Other Accession	NP_055830
Antigen Type	Synthetic Peptide
Bio Background	KDM4B is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20' and only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Bio References	Yang, J., et al. Cancer Res. 70(16):6456-6466(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Beyer, S., et al. J. Biol. Chem. 283(52):36542-36552(2008) Pollard, P.J., et al. Biochem. J. 416(3):387-394(2008) Katoh, Y., et al. Int. J. Mol. Med. 20(2):269-273(2007)
Gene ID	23030
Gene Name	KDM4B
Reactivity	H
Calculated MW	121897
Antigen Region	428-459
Antigen Source	HUMAN
Target/Specificity	This JMJD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-459 amino acids from the N-terminal region of human JMJD2B.
NCBI Accession	NP_055830.1

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Amount: 80 ul

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