Comparison

MMP1 Antibody (Center)

Manufacturer Abcepta
Category
Type Antibody Primary
Specific against other
Isotype Ig
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications WB, IF, IHC-P
Amount 400 ul
Host Rabbit
Item no. ABC-AP11874c
eClass 6.1 32160702
eClass 9.0 32160702
Available
Primary Accession
P03956
Antigen Type
Synthetic Peptide
Application
IF, IHC-P, WB
Bio Background
Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. This gene encodes a secreted enzyme
which breaks down the interstitial collagens, types I, II, and III.
The gene is part of a cluster of MMP genes which localize to
chromosome 11q22.3. Alternative splicing results in multiple
transcript variants.
Bio References
Beshir, A.B., et al. Cancer Lett. 299(2):137-149(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Malik, N., et al. J. Neurooncol. (2010) In press :
Skorupski, P., et al. Ginekol. Pol. 81(8):594-599(2010)
Mossbock, G., et al. Mol. Vis. 16, 1764-1770 (2010) :
Clonality
Polyclonal
Clone/Animal Names
RB18908
Gene ID
4312
Gene Name
MMP1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Confocal immunofluorescent analysis of MMP1 Antibody (Center) (Cat#AP11874c) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1
IF
Dilution image 1
1:10~50
Legend image 2
MMP1 Antibody (Center) (Cat. #AP11874c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the MMP1 antibody detected the MMP1 protein (arrow).
Type image 2
WB
Dilution image 2
1:1000
Legend image 3
MMP1 Antibody (Center) (Cat. #AP11874c)immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3
IHC-P
Dilution image 3
1:50~100
Other Accession
NP_002412
Isotype
Rabbit Ig
Calculated MW
54007
Antigen Region
317-347
Antigen Source
HUMAN
Target/Specificity
This MMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-347 amino acids from the Central region of human MMP1.
NCBI Accession
NP_002412.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close