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PTGS2 Antibody (Center P378)

PTGS2 Antibody (Center P378)

Item no.	ABC-AP11553C
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	COX-2, COX2, PTGS2, Prostaglandin G/H synthase 2, Cyclooxygenase-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, PGH synthase 2, PGHS-2
Available
Primary Accession	P35354
Antigen Type	Synthetic Peptide
Application	WB, IHC-P, IF
Bio Background	Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Bio References	Duggan, K.C., et al. J. Biol. Chem. 285(45):34950-34959(2010) Feher, A., et al. Am J Geriatr Psychiatry 18(11):983-987(2010) Wang, C.H., et al. Anticancer Res. 30(9):3649-3653(2010) Han, E.H., et al. J. Toxicol. Environ. Health Part A 73 (21-22), 1451-1464 (2010) : Cao, H., et al. Tohoku J. Exp. Med. 222(1):15-21(2010)
Clonality	Polyclonal
Clone/Animal Names	RB17409
Gene ID	5743
Gene Name	PTGS2 (HGNC:9605)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of PTGS2 Antibody (Center P378) (Cat. #AP11553c) with A549 cell followed by Alexa Fluor® 489-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	PTGS2 Antibody (Center P378) (Cat. #AP11553c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PTGS2 antibody detected the PTGS2 protein (arrow).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Anti-PTGS2 Antibody (Center P378) at 1:2000 dilution + HACAT whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 67 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 3	WB
Dilution image 3	1:2000
Legend image 4	PTGS2 Antibody (Center P378) (Cat. #AP11553c)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTGS2 Antibody (Center P378) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 4	IHC-P
Dilution image 4	1:10~50
Other Accession	NP_000954.1
Isotype	Rabbit IgG
Calculated MW	68996
Antigen Region	363-391
Antigen Source	HUMAN
Target/Specificity	This PTGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-391 amino acids from the Central region of human PTGS2.
NCBI Accession	NP_000954.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/8/2024

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