Item no. |
ABC-AP11441a-ev-80ul |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
Western Blot, Flow cytometry |
Clone |
RB55378 |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1, CRHR1, CRFR, CRFR1, CRHR |
Available |
|
Primary Accession |
P34998 |
Other Accession |
P35353; NP_001138618.1; NP_004373.2 |
Antigen Type |
Synthetic Peptide |
Bio Background |
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. |
Bio References |
Karteris, E., et al. Endocrinology 151(10):4959-4968(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Hillhouse, E.W., et al. Endocr. Rev. 27(3):260-286(2006) |
Gene ID |
104909134; 1394 |
Gene Name |
CRHR1 |
Reactivity |
H |
Predicted |
Rat |
Calculated MW |
50719 |
Antigen Region |
88-119 |
Antigen Source |
HUMAN |
Target/Specificity |
This CRFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-119 amino acids from human CRFR1. |
NCBI Accession |
NP_001138618.1; NP_001138619.1; NP_001138620.1; NP_001243228.1; NP_004373.2 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.