Item no. |
ABC-AP11227c |
Manufacturer |
Abcepta
|
Amount |
400 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, FC |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
DUOX2, LNOX2, THOX2, Dual oxidase 2, Large NOX 2, Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, Thyroid oxidase 2, p138 thyroid oxidase, 1111- |
Available |
|
Primary Accession |
Q9NRD8 |
Antigen Type |
Synthetic Peptide |
Application |
FC, WB |
Bio Background |
The protein encoded by this gene is a glycoprotein and amember of the NADPH oxidase family. The synthesis of thyroidhormone is catalyzed by a protein complex located at the apicalmembrane of thyroid follicular cells. This complex contains aniodide transporter, thyroperoxidase, and a peroxide generatingsystem that includes this encoded protein and DUOX1. This proteinis known as dual oxidase because it has both a peroxidase homologydomain and a gp91phox domain. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Salmeen, A., et al. Oncogene 29(31):4473-4484(2010)Linderholm, A.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (2), L215-L221 (2010) :Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Hill, T. III, et al. Biochem. Biophys. Res. Commun. 395(2):270-274(2010) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB19278 |
Gene ID |
50506 |
Gene Name |
DUOX2 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
DUOX2 Antibody (Center) (Cat. #AP11227c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DUOX2 antibody detected the DUOX2 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
DUOX2 Antibody (Center) (Cat. #AP11227c) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 2 |
FC |
Dilution image 2 |
1:10~50 |
Other Accession |
NP_054799 |
Isotype |
Rabbit Ig |
Calculated MW |
175364 |
Antigen Region |
513-542 |
Antigen Source |
HUMAN |
Target/Specificity |
This DUOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2. |
NCBI Accession |
NP_054799.4 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.