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DUOX2 Antibody (Center)

DUOX2 Antibody (Center)

Item no.	ABC-AP11227c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DUOX2, LNOX2, THOX2, Dual oxidase 2, Large NOX 2, Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, Thyroid oxidase 2, p138 thyroid oxidase, 1111-
Available
Primary Accession	Q9NRD8
Antigen Type	Synthetic Peptide
Application	FC, WB
Bio Background	The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Bio References	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Salmeen, A., et al. Oncogene 29(31):4473-4484(2010) Linderholm, A.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (2), L215-L221 (2010) : Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010) Hill, T. III, et al. Biochem. Biophys. Res. Commun. 395(2):270-274(2010)
Clonality	Polyclonal
Clone/Animal Names	RB19278
Gene ID	50506
Gene Name	DUOX2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	DUOX2 Antibody (Center) (Cat. #AP11227c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DUOX2 antibody detected the DUOX2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	DUOX2 Antibody (Center) (Cat. #AP11227c) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2	FC
Dilution image 2	1:10~50
Other Accession	NP_054799
Isotype	Rabbit Ig
Calculated MW	175364
Antigen Region	513-542
Antigen Source	HUMAN
Target/Specificity	This DUOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2.
NCBI Accession	NP_054799.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/8/2024

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