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IGF2 Antibody (Center R54)

IGF2 Antibody (Center R54)

Manufacturer	Abcepta
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Carcinoma Sarcoma Cell Biology Cell Culture Cytokines Flow Cytometry Immunohistochemistry Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Polyclonal
Specific against	other
Clone	RB53634
Isotype	Ig
Applications	Western Blot, Flow cytometry, Immunohistochemistry
Amount	50 ul
Host	Rabbit
Item no.	ABC-AP11220c-ev-50ul
Targets	INS ;;IGF1;;IGF2
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Insulin-like growth factor II, IGF-II, Somatomedin-A, Insulin-like growth factor II, Insulin-like growth factor II Ala-25 Del, Preptin, IGF2
Primary Accession	P01344
Other Accession	NP_000603
Antigen Type	Synthetic Peptide
Bio Background	This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Bio References	Adkins, R.M., et al. Pediatr. Res. 68(5):429-434(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Li, J., et al. Mol. Biol. Rep. (2010) In press : Hsieh, Y.Y., et al. Anticancer Res. 30(6):2203-2208(2010) Turan, N., et al. PLoS Genet. 6 (7), E1001033 (2010) :
Gene ID	3481
Gene Name	IGF2
Reactivity	H, M
Calculated MW	20140
Antigen Region	39-68
Antigen Source	HUMAN
Target/Specificity	This IGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human IGF2.
NCBI Accession	NP_000603.1; NP_001007140.2; NP_001121070.1

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Amount: 50 ul

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