INHBA Antibody (N-term)

Synthetic Peptide

The inhibin beta A subunit joins the alpha subunit to form
a pituitary FSH secretion inhibitor. Inhibin has been shown to
regulate gonadal stromal cell proliferation negatively and to have
tumor-suppressor activity. In addition, serum levels of inhibin
have been shown to reflect the size of granulosa-cell tumors and
can therefore be used as a marker for primary as well as recurrent
disease. Because expression in gonadal and various extragonadal
tissues may vary severalfold in a tissue-specific fashion, it is
proposed that inhibin may be both a growth/differentiation factor
and a hormone. Furthermore, the beta A subunit forms a homodimer,
activin A, and also joins with a beta B subunit to form a
heterodimer, activin AB, both of which stimulate FSH secretion.
Finally, it has been shown that the beta A subunit mRNA is
identical to the erythroid differentiation factor subunit mRNA and
that only one gene for this mRNA exists in the human genome.

Polyclonal

3624

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Confocal immunofluorescent analysis of INHBA Antibody (N-term)(Cat#AP11126a) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

1:10~50

WB

INHBA Antibody (N-term) (Cat. #AP11126a)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of INHBA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

1:10~50

FC

P18331; Q04998; P07995; NP_002183.1; P55102; P43032

Rabbit Ig

85-112

This INHBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 amino acids from the N-terminal region of human INHBA.