Item no. |
ABC-AP10707a |
Manufacturer |
Abcepta
|
Amount |
400 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, FC |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
HIF2A, HLF, EPAS1, BHLHE73, MOP2, PASD2, Endothelial PAS domain-containing protein 1, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, HIF-1-alpha-like factor, Hypoxia-inducible factor 2-alpha, Member of PAS protein 2, EPAS-1, bHLHe73, HIF-2-alpha, HIF2-alpha, PAS domain-containing protein 2 |
Available |
|
Primary Accession |
Q99814 |
Antigen Type |
Synthetic Peptide |
Application |
FC, WB |
Bio Background |
This gene encodes a transcription factor involved in theinduction of genes regulated by oxygen, which is induced as oxygenlevels fall. The encoded protein contains a basic-helix-loop-helixdomain protein dimerization domain as well as a domain found inproteins in signal transduction pathways which respond to oxygenlevels. Mutations in this gene are associated with erythrocytosisfamilial type 4. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Yi, X., et al. Science 329(5987):75-78(2010)Bougatef, F., et al. PLoS ONE 5 (8), E12265 (2010) :Hossein Ghaderian, S.M., et al. Pathology 42(5):446-453(2010)Mowat, F.M., et al. PLoS ONE 5 (6), E11103 (2010) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB28543 |
Gene ID |
2034 |
Gene Name |
EPAS1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
EPAS1 Antibody (N-term) (Cat. #AP10707a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the EPAS1 antibody detected the EPAS1 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
EPAS1 Antibody (N-term) (Cat. #AP10707a) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 2 |
FC |
Dilution image 2 |
1:10~50 |
Other Accession |
NP_001421.2 |
Isotype |
Rabbit Ig |
Calculated MW |
96459 |
Antigen Region |
124-150 |
Antigen Source |
HUMAN |
Target/Specificity |
This EPAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-150 amino acids from the N-terminal region of human EPAS1. |
NCBI Accession |
NP_001421.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.