Item no. |
ABC-AP10161C-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
AADAT, mitochondrial, KAT2, Kynurenine/alpha-aminoadipate aminotransferase, 2-aminoadipate transaminase, KAT/AadAT, Kynurenine aminotransferase II, 2-aminoadipate aminotransferase, Alpha-aminoadipate aminotransferase, Kynurenine--oxoglutarate aminotransferase II, Kynurenine--oxoglutarate transaminase II, AadAT, Kynurenine--oxoglutarate transaminase 2 |
Available |
|
Primary Accession |
Q8N5Z0 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
This gene encodes a protein that is highly similar tomouse and rat kynurenine aminotransferase II. The rat protein is ahomodimer with two transaminase activities. One activity is thetransamination of alpha-aminoadipic acid, a final step in thesaccaropine pathway which is the major pathway for L-lysinecatabolism. The other activity involves the transamination ofkynurenine to produce kynurenine acid, the precursor of kynurenicacid which has neuroprotective properties. Two alternativetranscripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. |
Bio References |
Han, Q., et al. Biosci. Rep. 28(4):205-215(2008)Rossi, F., et al. J. Biol. Chem. 283(6):3559-3566(2008)Han, Q., et al. J. Biol. Chem. 283(6):3567-3573(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Goh, D.L., et al. Mol. Genet. Metab. 76(3):172-180(2002) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB22817 |
Gene ID |
51166 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
AADAT Antibody (Center) (Cat. #AP10161c) western blot analysis in HepG2, Y79 cell line lysates (35ug/lane).This demonstrates the AADAT antibody detected the AADAT protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_872603.1; NP_057312.1 |
Isotype |
Rabbit Ig |
Calculated MW |
47352 |
Antigen Region |
196-224 |
Antigen Source |
HUMAN |
Target/Specificity |
This AADAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human AADAT. |
NCBI Accession |
NP_057312.1; NP_872603.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.