Item no. |
ABC-AO2370a |
Manufacturer |
Abcepta
|
Amount |
0.1mg |
Category |
|
Type |
Antibody Primary |
Applications |
WB, FC, IHC, ICC, ELISA |
Clone |
1B12H2 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CD289 |
Available |
|
Primary Accession |
Q9NR96 |
Application |
WB, IHC, FC, ICC, E |
Bio References |
1.J Virol. 2015 Nov; 89(22):11396-405. ; 2.Immunogenetics. 2014 Dec; 66(12):675-81.; |
Clonality |
Monoclonal |
Gene ID |
54106 |
Gene Name |
TLR9 |
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H |
Legend image 1 |
Black line: Control Antigen (100 ng); Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) |
Type image 1 |
E |
Legend image 2 |
Western blot analysis using TLR9 mAb against human TLR9 (AA: 868-1016) recombinant protein. (Expected MW is 43.4 kDa) |
Type image 2 |
WB |
Legend image 3 |
Western blot analysis using TLR9 mAb against HEK293 (1) and TLR9 (AA: 868-1016)-hIgGFc transfected HEK293 (2) cell lysate. |
Type image 3 |
WB |
Legend image 4 |
Flow cytometric analysis of A549 cells using TLR9 mouse mAb (green) and negative control (red). |
Type image 4 |
FC |
Legend image 5 |
Immunofluorescence analysis of SK-OV-3 cells using TLR9 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher |
Type image 5 |
ICC |
Legend image 6 |
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using TLR9 mouse mAb with DAB staining. |
Type image 6 |
IHC |
Legend image 7 |
Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using TLR9 mouse mAb with DAB staining. |
Type image 7 |
IHC |
Isotype |
Mouse IgG2a |
Calculated MW |
115860 |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Description |
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.; |
|
Clone: 1B12H2 |
Immunogen |
Purified recombinant fragment of human TLR9 (AA: 868-1016) expressed in E. Coli. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.