Item no. |
ABC-AO1842a |
Manufacturer |
Abcepta
|
Amount |
100 ul |
Category |
|
Type |
Antibody Primary |
Applications |
WB, ELISA |
Clone |
1G4C5 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
DCN, Bone proteoglycan II, PG-S2, PG40, SLRR1B, Decorin |
Available |
|
Primary Accession |
P07585 |
Antigen Type |
Recombinant Protein |
Application |
WB, E |
Bio Background |
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. ; ; |
Bio References |
1. PLoS One. 2012; 7(9):e45559. 2. Hum Reprod. 2012 Nov; 27(11):3249-58. |
Clonality |
Monoclonal |
Gene ID |
1634 |
Gene Name |
DCN |
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H |
Legend image 1 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); |
Type image 1 |
E |
Dilution image 1 |
1/10000 |
Legend image 2 |
Figure 1: Western blot analysis using DCN mAb against human DCN recombinant protein. (Expected MW is 32.5 kDa) |
Type image 2 |
WB |
Dilution image 2 |
1/500 - 1/2000 |
Legend image 3 |
Figure 2: Western blot analysis using DCN mAb against HEK293 (1) and DCN (AA: 263-324)-hIgGFc transfected HEK293 (2) cell lysate. |
Type image 3 |
WB |
Dilution image 3 |
1/500 - 1/2000 |
Isotype |
IgG1 |
Calculated MW |
39747 |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Description |
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. |
|
Clone: 1G4C5 |
Immunogen |
Purified recombinant fragment of human DCN (AA: 263-324) expressed in E. Coli. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.