ALCAM Antibody

Recombinant Protein

This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.  ;

Monoclonal

ALCAM

H, M

E

Figure 1: Western blot analysis using ALCAM mAb against human ALCAM recombinant protein. (Expected MW is 44.9 kDa)

1/500 - 1/2000

WB

Figure 3: Western blot analysis using ALCAM mouse mAb against NIH/3T3 cell lysate.

1/500 - 1/2000

FC

Figure 5: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using ALCAM mouse mAb with DAB staining.

1/200 - 1/1000

IHC

IgG2b

Purified antibody in PBS with 0.05% sodium azide

Clone: 4H9A5