Item no. |
ABC-AO1598a |
Manufacturer |
Abcepta
|
Amount |
100 ul |
Category |
|
Type |
Antibody Primary |
Applications |
WB, FC, IHC, ELISA |
Clone |
2H9 |
Specific against |
other |
Host |
Mouse |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
IRAK-4, IRAK4, Interleukin-1 receptor-associated kinase 4, Renal carcinoma antigen NY-REN-64, 2.7.11.1 |
Available |
|
Primary Accession |
Q9NWZ3 |
Antigen Type |
Recombinant Protein |
Application |
WB, IHC, FC, E |
Bio References |
1. J Biol Chem. 2010 Jun 11; 285(24):18276-82. 2. Scand J Immunol. 2009 Sep; 70(3):264-76. |
Clonality |
Monoclonal |
Gene ID |
51135 |
Gene Name |
IRAK4 |
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H, M, Pr |
Legend image 1 |
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); |
Type image 1 |
E |
Dilution image 1 |
1/10000 |
Legend image 2 |
Figure 1: Western blot analysis using IRAK4 mAb against human IRAK4 (AA: 21-198) recombinant protein. (Expected MW is 45.4 kDa) |
Type image 2 |
WB |
Dilution image 2 |
1/500 - 1/2000 |
Legend image 3 |
Figure 2: Western blot analysis using IRAK4 mouse mAb against THP-1 (1), Hela (2), K562 (3), MCF-7 (4), RAW264.7 (5), Jurkat (6) and Cos7 (7) cell lysate. |
Type image 3 |
WB |
Dilution image 3 |
1/500 - 1/2000 |
Legend image 4 |
Figure 3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using IRAK4 mouse mAb with DAB staining. |
Type image 4 |
IHC |
Dilution image 4 |
1/200 - 1/1000 |
Legend image 5 |
Figure 4: Immunohistochemical analysis of paraffin-embedded human kidney cancer tissues using IRAK4 mouse mAb with DAB staining. |
Type image 5 |
IHC |
Dilution image 5 |
1/200 - 1/1000 |
Legend image 6 |
Figure 5: Flow cytometric analysis of Hela cells using IRAK4 mouse mAb (blue) and negative control (red). |
Type image 6 |
FC |
Dilution image 6 |
1/200 - 1/400 |
Isotype |
IgG1 |
Calculated MW |
51530 |
Formulation |
Ascitic fluid containing 0.03% sodium azide. |
Description |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
|
Clone: 2H9 |
Immunogen |
Purified recombinant fragment of human IRAK4 expressed in E. Coli. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.