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EIF2A Antibody

EIF2A Antibody

Item no.	ABC-AM8594b-ev-50ul
Manufacturer	Abcepta
Amount	50 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	Western Blot
Specific against	other
Host	Mouse
Isotype	IgG2b kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A
Available
Primary Accession	P05198
Antigen Type	Recombinant Protein
Bio Background	Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Bio References	Ernst H., et al.J. Biol. Chem. 262:1206-1212(1987). Langland J.O., et al.Virology 324:419-429(2004). Paytubi S., et al.Biochem. J. 409:223-231(2008). Montero H., et al.J. Virol. 82:1496-1504(2008). Mayya V., et al.Sci. Signal. 2:RA46-RA46(2009).
Gene ID	1965
Gene Name	EIF2S1 (HGNC:3265)
Reactivity	H, M, Rat
Calculated MW	36112
Antigen Source	HUMAN
Target/Specificity	This EIF2A antibody is generated from a mouse immunized with a recombinant protein of human EIF2A.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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