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ENPP2 / Autotaxin Antibody (aa698-712)

ENPP2 / Autotaxin Antibody (aa698-712)

Item no.	ABC-ALS16150
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA, IHC-P
Specific against	other
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ENPP2, ATX, LysoPLD, PDNP2, Autotaxin, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, Extracellular lysophospholipase D, 3.1.4.39
Available
Primary Accession	Q13822
Antigen Type	Synthetic peptide
Application	WB, IHC-P, E
Bio Background	Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility- related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Bio References	Murata J., et al.J. Biol. Chem. 269:30479-30484(1994). Kawagoe H., et al.Genomics 30:380-384(1995). Lee H.Y., et al.Biochem. Biophys. Res. Commun. 218:714-719(1996). van Meeteren L.A., et al.J. Biol. Chem. 280:21155-21161(2005). Giganti A., et al.J. Biol. Chem. 283:7776-7789(2008).
Clonality	Polyclonal
Gene ID	5168
Gene Name	ENPP2
Subtitle	Goat Polyclonal Antibody
Reactivity	H, Pr
Legend image 1	ENPP2 antibody (0.3 ug/ml) staining of Human Placenta lysate (35 ug protein in RIPA buffer).
Type image 1	WB
Legend image 2	Anti-ENPP2 / Autotaxin antibody IHC staining of human brain, cortex.
Type image 2	IHC
Legend image 3	Anti-ENPP2 / Autotaxin antibody IHC staining of human liver.
Type image 3	IHC
Calculated MW	98994
Target/Specificity	Human ENPP2 / Autotaxin. This antibody is expected to recognize all reported isoforms (NP_006200.3; NP_001035181.1, NP_001124335.1).
Purification	Immunoaffinity purified
Concentration (mg/ml)	0.5 mg/ml
Reconstitution & Storage	Store at -20°C. Minimize freezing and thawing.
Dilution	ELISA (1:128000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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