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PTPN11 / SHP-2 / NS1 Antibody (C-Terminus)

PTPN11 / SHP-2 / NS1 Antibody (C-Terminus)

Item no.	ABC-ALS13396
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA, IHC-P
Specific against	other
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PTPN11, PTP2C, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, SHP-2, PTP-2C, PTP-1D, Shp2, 3.1.3.48
Available
Primary Accession	Q06124
Antigen Type	Synthetic peptide
Application	WB, IHC-P, E
Bio Background	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
Bio References	Adachi M., et al.FEBS Lett. 314:335-339(1992). Freeman R.M. Jr., et al.Proc. Natl. Acad. Sci. U.S.A. 89:11239-11243(1992). Bastien L., et al.Biochem. Biophys. Res. Commun. 196:124-133(1993). Ahmad S., et al.Proc. Natl. Acad. Sci. U.S.A. 90:2197-2201(1993). Vogel W., et al.Science 259:1611-1614(1993).
Clonality	Polyclonal
Gene ID	5781
Gene Name	PTPN11
Subtitle	Goat Polyclonal Antibody
Reactivity	H, Rb, Pr, C, Hs, X, B
Legend image 1	Anti-PTPN11 antibody IHC of human brain, cerebellum.
Type image 1	IHC
Legend image 2	Anti-PTPN11 antibody IHC of human kidney.
Type image 2	IHC
Calculated MW	68011
Target/Specificity	Human PTPN11.
Purification	Immunoaffinity purified
Concentration (mg/ml)	0.5 mg/ml
Reconstitution & Storage	Store at -20°C. Minimize freezing and thawing.
Dilution	ELISA (1:32000), IHC-P (3.75 µg/ml), WB (1-3 µg/ml)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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