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TIRAP Antibody (C-Terminus)

TIRAP Antibody (C-Terminus)

Item no.	ABC-ALS11722
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TIRAP, MAL, MyD88 adapter-like protein, Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88-2
Available
Primary Accession	P58753
Antigen Type	Synthetic peptide
Application	WB, IHC-P
Bio Background	Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
Bio References	Fitzgerald K.A., et al.Nature 413:78-83(2001). Horng T., et al.Nat. Immunol. 2:835-841(2001). Kirk P.B., et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases. Hardy M.P., et al.Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. Nakajima T., et al.Immunogenetics 60:727-735(2008).
Clonality	Polyclonal
Gene ID	114609
Gene Name	TIRAP
Subtitle	Rabbit Polyclonal Antibody
Reactivity	H, M, Rat
Legend image 1	Anti-TIRAP antibody IHC of human heart.
Type image 1	IHC
Legend image 2	Anti-TIRAP antibody IHC of human kidney.
Type image 2	IHC
Calculated MW	23883
Target/Specificity	peptide corresponding to 15 amino acids near the C-terminus of mouse TIRAP
Purification	Ion exchange chromatography
Concentration (mg/ml)	1 mg/ml
Reconstitution & Storage	Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Dilution	IHC-P (5 µg/ml), WB (0.5-2 µg/ml),

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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