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DNASE2 / DNase II Antibody (aa347-360)

DNASE2 / DNase II Antibody (aa347-360)

Item no.	ABC-ALS11451
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DNASE2, DNASE2A, DNL2, DNase II alpha, R31240_2, Acid DNase, Deoxyribonuclease II alpha, Deoxyribonuclease-2-alpha, Lysosomal DNase II, 3.1.22.1
Available
Primary Accession	O00115
Antigen Type	Synthetic peptide
Application	WB, IHC-P
Bio Background	Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Bio References	Yasuda T., et al.Ann. Hum. Genet. 62:299-305(1998). Shiokawa D., et al.Biochem. Biophys. Res. Commun. 247:864-869(1998). Baker K.P., et al.Gene 215:281-289(1998). Krieser R.J., et al.J. Biol. Chem. 273:30909-30914(1998). Yasuda T., et al.J. Biol. Chem. 273:2610-2616(1998).
Clonality	Polyclonal
Gene ID	1777
Gene Name	DNASE2
Subtitle	Rabbit Polyclonal Antibody
Reactivity	H
Legend image 1	Western blot of DNase II in human spleen tissue lysate in the absence (lane 1) or presence (lane...
Type image 1	WB
Legend image 2	Anti-DNASE2 / DNase II antibody IHC of human thymus.
Type image 2	IHC
Legend image 3	Anti-DNASE2 / DNase II antibody IHC of human brain, cerebellum.
Type image 3	IHC
Calculated MW	39581
Target/Specificity	peptide corresponding to amino acids 347 to 360 of human DNase II precursor (2-4)
Purification	Immunoaffinity purified
Concentration (mg/ml)	1 mg/ml
Reconstitution & Storage	Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Dilution	IHC-P (5 µg/ml), WB (1:500-1:1000),

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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