Item no. |
ABC-AI16203 |
Manufacturer |
Abcepta
|
Amount |
50 ug |
Category |
|
Type |
Antibody Primary |
Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CHRNA9, NACHRA9, Neuronal acetylcholine receptor subunit alpha-9, Nicotinic acetylcholine receptor subunit alpha-9, NACHR alpha-9 |
Available |
|
Primary Accession |
Q9UGM1 |
Application |
WB |
Bio Background |
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed: 11752216, PubMed: 25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed: 11752216, PubMed: 25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed: 11021840). |
Bio References |
Sgard F., et al.Mol. Pharmacol. 61:150-159(2002).Lustig L.R., et al.Cytogenet. Genome Res. 98:154-159(2002).Hillier L.W., et al.Nature 434:724-731(2005).Nguyen V.T., et al.Am. J. Pathol. 157:1377-1391(2000).Peng H., et al.Life Sci. 76:263-280(2004). |
Clonality |
Polyclonal |
Gene ID |
55584 |
Gene Name |
CHRNA9 |
Subtitle |
Rabbit Polyclonal Antibody |
Reactivity |
M, Rb, Hs, B, Gp, Dog |
Legend image 1 |
WB Suggested Anti-CHRNA9 Antibody Titration: 0.0625?g/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate |
Type image 1 |
WB |
Other Accession |
NM_017581; NP_060051 |
Predicted |
M, Rb, Hs, B, Gp, Dog |
Calculated MW |
54807 |
Immunogen |
The immunogen for anti-CHRNA9 antibody: synthetic peptide directed towards the N terminal of human CHRNA9 |
Purification |
Affinity Purified |
Protein Size |
479 |
Partner Proteins |
CHRNA4, CHRNA2, CHRNA4, CRELD2 |
Nucleotide Accession Num |
NM_017581 |
Protein Accession Num |
NP_060051 |
Alias Symbol |
NACHRA9, HSA243342 |
Reconstitution & Storage |
Add 50 ul of distilled water. Final anti-CHRNA9 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.