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Nucleolin (Marker of Human Cells) Antibody - With BSA and Azide

Nucleolin (Marker of Human Cells) Antibody - With BSA and Azide

Item no.	ABC-AH11987-U0020
Manufacturer	Abcepta
Amount	20 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, IF, IHC
Clone	364-5 + NCL/902
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NCL, Nucleolin, Protein C23
Available
Primary Accession	P19338
Application	WB, IHC, IF, FC
Bio Background	Recognizes a protein of ~76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.?This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.
Bio References	Fujiki H, Watanabe T, Suganuma M. Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands. J Cancer Res Clin Oncol. 2014; 140(5):689-99. \| Qiu W, Zhou F, Zhang Q, Sun X, Shi X, Liang Y, Wang X, Yue L. Overexpression of nucleolin and different expression sites both related to the prognosis of gastric cancer. APMIS. 2013; 121(10):919-25.
Clonality	Monoclonal
Gene ID	4691
Gene Name	NCL
Subtitle	Mouse Monoclonal Antibody [Clone 364-5 + NCL/902 ]
Reactivity	H
Legend image 1	Formalin-fixed, paraffin-embedded human Tonsil stained with Nucleolin Monoclonal Antibody (364-5 + NCL/902
Type image 1	IHC
Legend image 2	Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with Nucleolin Monoclonal Antibody (364-5 + NCL/902).
Type image 2	IHC
Legend image 3	Formalin-fixed, paraffin-embedded human Uterus stained with Nucleolin Monoclonal Antibody (364-5 + NCL/902).
Type image 3	IHC
Legend image 4	Formalin-fixed, paraffin-embedded human Bladder Carcinoma stained with Nucleolin Monoclonal Antibody (364-5 + NCL/902).
Type image 4	IHC
Legend image 5	Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with Nucleolin Monoclonal Antibody (364-5 + NCL/902).
Type image 5	IHC
Legend image 6	Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with AF488 Conjugate of Nucleolin Monoclonal Antibody (364-5 + NCL/902).
Type image 6	IHC
Other Accession	4691, 79110
	Clone: 364-5 + NCL/902

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 9/6/2024