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Goat Anti-NEFM / NF-M Antibody

Goat Anti-NEFM / NF-M Antibody

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Applications	WB, ELISA
Amount	100 ug
Host	Goat
Item no.	ABC-AF2197a
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	P07197
Antigen Type	Synthetic Peptide
Application	WB, E
Bio Background	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Bio References	Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030. Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 Apr 8. PMID 20381070. Human variation in alcohol response is influenced by variation in neuronal signaling genes. Joslyn G, et al. Alcohol Clin Exp Res, 2010 May. PMID 20201926. Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. Martins-de-Souza D, et al. J Neural Transm, 2009 Mar. PMID 19034380. Association of the dopamine receptor interacting protein gene, NEF3, with early response to antipsychotic medication. Strous RD, et al. Int J Neuropsychopharmacol, 2007 Jun. PMID 16734940.
Clonality	Polyclonal
Gene ID	4741
Gene Name	NEFM
Subtitle	Peptide-affinity purified goat antibody
Reactivity	M
Legend image 1	AF2197a (0.03 µg/ml) staining of Mouse Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1	WB
Other Accession	NP_001099011; 4741; 18040 (mouse); 24588 (rat);
Predicted	H, Rat, Pig, Dog, Cow
Concentration (mg/ml)	100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 8/2/2024