Comparison

Goat Anti-Syntrophin gamma 2 Antibody

Item no. ABC-AF2060a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products SNTG2, G2SYN, SYN5, Syntrophin-5, Gamma-2-syntrophin
Available
Primary Accession
Q9NY99
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
Bio References
Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations. Yamakawa H, et al. Biochem Biophys Res Commun, 2007 Mar 30. PMID 17292328.
Generation and initial analysis of more than 15, 000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction. Ou Y, et al. J Biol Chem, 2003 Jan 17. PMID 12429735.
Creation of genome-wide protein expression libraries using random activation of gene expression. Harrington JJ, et al. Nat Biotechnol, 2001 May. PMID 11329013.
Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells. Piluso G, et al. J Biol Chem, 2000 May 26. PMID 10747910.
Clonality
Polyclonal
Gene ID
54221
Gene Name
SNTG2
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H
Legend image 1
AF2060a (0.3 µg/ml) staining of Human Duodenum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1
WB
Other Accession
NP_061841; 54221;
Concentration (mg/ml)
100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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