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Goat Anti-STAM2 Antibody

Goat Anti-STAM2 Antibody

Item no.	ABC-AF2038a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA
Specific against	other
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	STAM2, HBP, Signal transducing adapter molecule 2, Hrs-binding protein, STAM-2
Available
Primary Accession	O75886
Antigen Type	Synthetic Peptide
Application	WB, E
Bio Background	The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
Bio References	PTP1B targets the endosomal sorting machinery: dephosphorylation of regulatory sites on the endosomal sorting complex required for transport component STAM2. Stuible M, et al. J Biol Chem, 2010 Jul 30. PMID 20504764. An empirical framework for binary interactome mapping. Venkatesan K, et al. Nat Methods, 2009 Jan. PMID 19060904. STAM adaptor proteins interact with COPII complexes and function in ER-to-Golgi trafficking. Rismanchi N, et al. Traffic, 2009 Feb. PMID 19054391. E3-independent monoubiquitination of ubiquitin-binding proteins. Hoeller D, et al. Mol Cell, 2007 Jun 22. PMID 17588522. Rin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradation. Kong C, et al. J Biol Chem, 2007 May 18. PMID 17403676.
Clonality	Polyclonal
Gene ID	10254
Gene Name	STAM2
Subtitle	Peptide-affinity purified goat antibody
Reactivity	H
Legend image 1	AF2038a (1 µg/ml) staining of Human Spleen lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1	WB
Other Accession	NP_005834; 10254; 56324 (mouse);
Predicted	M, Dog
Concentration (mg/ml)	100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/6/2024