Comparison

Goat Anti-HSPC150 / UBE2T Antibody

Manufacturer Abcepta
Category
Type Antibody Primary
Specific against other
Applications WB, ELISA
Amount 100 ug
Host Goat
Item no. ABC-AF1545a
eClass 6.1 32160702
eClass 9.0 32160702
Available
Primary Accession
Q9NPD8
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3) (Machida et al., 2006 [PubMed 16916645]).
Bio References
Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells. Ueki T, et al. Cancer Res, 2009 Nov 15. PMID 19887602.
FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL. Longerich S, et al. J Biol Chem, 2009 Aug 28. PMID 19589784.
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. Alpi AF, et al. Mol Cell, 2008 Dec 26. PMID 19111657.
Elevated expression of UBE2T in lung cancer tumors and cell lines. Hao J, et al. Tumour Biol, 2008. PMID 18667844.
Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
Clonality
Polyclonal
Gene ID
29089
Gene Name
UBE2T
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H
Legend image 1
AF1545a (0.1 µg/ml) staining of K562 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1
WB
Other Accession
NP_054895; 29089;
Concentration (mg/ml)
100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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