Comparison

Goat Anti-FRAT2 / GSK-3 Antibody

Item no. ABC-AF1442a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products FRAT2, GSK-3-binding protein FRAT2, Frequently rearranged in advanced T-cell lymphomas 2, FRAT-2
Available
Primary Accession
O75474
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.
Bio References
Association between polymorphisms in Wnt signaling pathway genes and bone mineral density in postmenopausal Korean women. Lee DY, et al. Menopause, 2010 Sep-Oct. PMID 20613673.
Activation of glycogen synthase kinase-3 inhibits protein phosphatase-2A and the underlying mechanisms. Liu GP, et al. Neurobiol Aging, 2008 Sep. PMID 17433504.
FRAT-2 preferentially increases glycogen synthase kinase 3 beta-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation. Stoothoff WH, et al. J Biol Chem, 2005 Jan 7. PMID 15522877.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054.
Clonality
Polyclonal
Gene ID
23401
Gene Name
FRAT2
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H
Legend image 1
AF1442a staining (2 µg/ml) of Human Heart lysate (RIPA buffer, 30 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Type image 1
WB
Other Accession
NP_036215; 23401;
Concentration (mg/ml)
100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close