Item no. |
ABC-AF1429a |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Applications |
IHC, ELISA |
Specific against |
other |
Host |
Goat |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
TTF-2, FOXE1, FKHL15, FOXE2, HFKH4, HFKL5, TITF2, TTF2, Forkhead box protein E1, Forkhead box protein E2, Forkhead-related protein FKHL15, HNF-3/fork head-like protein 5, Thyroid transcription factor 2 |
Available |
|
Primary Accession |
O00358 |
Antigen Type |
Synthetic Peptide |
Application |
IHC, E |
Bio Background |
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I. |
Bio References |
Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate. Nikopensius T, et al. Birth Defects Res A Clin Mol Teratol, 2010 Jul 29. PMID 20672350.Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. Letra A, et al. Am J Med Genet A, 2010 Jul. PMID 20583170.MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate. Jagom脌gi T, et al. Eur J Oral Sci, 2010 Jun. PMID 20572854.Association between genetic variants of reported candidate genes or regions and risk of cleft lip with or without cleft palate in the polish population. Mostowska A, et al. Birth Defects Res A Clin Mol Teratol, 2010 Jul. PMID 20544801. |
Clonality |
Polyclonal |
Gene ID |
2304 |
Gene Name |
FOXE1 |
Subtitle |
Peptide-affinity purified goat antibody |
Reactivity |
H |
Legend image 1 |
AF1429a (2 µg/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. |
Type image 1 |
IHC |
Legend image 2 |
AF1429a (5 µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. |
Type image 2 |
IHC |
Other Accession |
NP_004464; 2304; |
Concentration (mg/ml) |
100ug/200ul |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.