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JMJD2a polyclonal antibody

JMJD2a polyclonal antibody

Item no.	ABC-ADN10247
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	JMJD2A, KDM4A, JHDM3A, JMJD2, KIAA0677, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, Lysine-specific demethylase 4A, 1.14.11.-
Available
Primary Accession	O75164
Application	WB, E
Bio Background	Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Bio References	Ishikawa K., et al.DNA Res. 5:169-176(1998). Gregory S.G., et al.Nature 441:315-321(2006). Gray S.G., et al.J. Biol. Chem. 280:28507-28518(2005). Zhang D., et al.Mol. Cell. Biol. 25:6404-6414(2005). Whetstine J.R., et al.Cell 125:467-481(2006).
Clonality	Polyclonal
Gene ID	9682
Gene Name	KDM4A
Subtitle	Purified Rabbit Polyclonal Antibody
Reactivity	H
Legend image 1	Determination of the antibody titer
Type image 1	E
Legend image 2	Western blot analysis using the antibody directed against JMJD2a
Type image 2	WB

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 9/6/2024

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