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Phospho-Bad (Ser136) antibody

Phospho-Bad (Ser136) antibody

Item no.	ABC-ABV11678-100
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter
Available
Primary Accession	Q92934
Application	WB, IHC, E
Bio Background	Bad is a member of the Bcl-2 family protein that selectively dimerize with Bcl-xL and Bcl-2 resulting in cell death. Survival factors such as IL-3 can inhibit the apoptotic activity of Bad by activating intracellular signaling pathways that result in the phosphorylation of Bad at Ser112 and Ser 136. Phosphorylation at these sites results in the binding of Bad to 14-3-3 proteins and the inhibition of Bad binding to Bcl-xL and Bcl-2. Recently, Akt has also been shown to promote cell survival via its ability to phosphorylate Bad at Ser136.
Clonality	Polyclonal
Gene ID	572
Gene Name	BAD
Subtitle	Purified Rabbit Polyclonal Antibody
Reactivity	H, M, Rat
Legend image 1	Western blot analysis of NIH/3T3 cells using Phospho-Bad(Ser136) Polyclonal antibody.
Type image 1	WB
Other Accession	Q61337 (Mouse); O35147 (Rat)
Concentration (mg/ml)	1mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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