Item no. |
ABC-ABO12798 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Lyophilized |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CCR-5, CCR5, CMKBR5, C-C chemokine receptor type 5, CHEMR13, HIV-1 fusion coreceptor, C-C CKR-5, CC-CKR-5, CD195 |
Available |
|
Primary Accession |
P51681 |
Application |
WB |
Clonality |
Polyclonal |
Gene ID |
1234 |
Reactivity |
H, M, Rat |
Legend image 1 |
Figure 1. Western blot analysis of CCR5 using anti-CCR5 antibody (ABO12798). |
Type image 1 |
WB |
Dilution image 1 |
0.1-0.5 µg/ml |
Calculated MW |
40524 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Description |
Rabbit IgG polyclonal antibody for CCR5 detection. Tested with WB in Human; Mouse; Rat. |
Protein Function |
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. |
Subcellular Localization |
Cell membrane. |
Tissue Specificity |
Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung. |
Contents |
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence of human CCR5 (YSGILKTLLRCRNEKKRHRAVRLIFT). |
Cross Reactivity |
No cross reactivity with other proteins. |
Storage |
At -20?C; for one year. After r?Constitution, at 4?C; for one month. It?Can also be aliquotted and stored frozen at -20?C; for a longer time. Avoid repeated freezing and thawing. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.