Item no. |
ABC-ABO11885 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Lyophilized |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
FOXM1, MPP2, WIN, FKHL16, HFH-11, HFH11, M-phase phosphoprotein 2, Forkhead box protein M1, Forkhead-related protein FKHL16, Hepatocyte nuclear factor 3 forkhead homolog 11, HNF-3/fork-head homolog 11, MPM-2 reactive phosphoprotein 2, Transcription factor Trident, Winged-helix factor from INS-1 cells |
Available |
|
Primary Accession |
Q08050 |
Application |
WB |
Clonality |
Polyclonal |
Gene ID |
2305 |
Reactivity |
H |
Legend image 1 |
Anti- FOXM1 antibody, ABO11885, Western blottingAll lanes: Anti FOXM1 (ABO11885) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: SW620 Whole Cell Lysate at 40ugLane 4: SKOV Whole Cell Lysate at 40ugLane 5: MCD-7 Whole Cell Lysate at 40ugPredicted bind size: 84KDObserved bind size: 84KD |
Type image 1 |
WB |
Dilution image 1 |
0.1-0.5 µg/ml |
Legend image 2 |
Anti- FOXM1 antibody, ABO11885, Western blottingAll lanes: Anti FOXM1 (ABO11885) at 0.5ug/mlWB: Recombinant Human FOXM1 Protein 0.5ngPredicted bind size: 36KDObserved bind size: 36KD |
Type image 2 |
WB |
Dilution image 2 |
0.1-0.5 µg/ml |
Calculated MW |
84283 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Description |
Rabbit IgG polyclonal antibody for Forkhead box protein M1(FOXM1) detection. Tested with WB in Human. |
Protein Function |
Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. . |
Subcellular Localization |
Nucleus. |
Tissue Specificity |
Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis. |
Protein Name |
Forkhead box protein M1 |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Immunogen |
E.coli-derived human FOXM1 recombinant protein (Position: A411-Q763). Human FOXM1 shares 75% and 76% amino acid (aa) sequences identity with mouse and rat FOXM1, respectively. |
Purification |
Immunogen affinity purified. |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Sequence Similarities |
Contains 1 fork-head DNA-binding domain. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.