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Anti-PSD95 Antibody

Anti-PSD95 Antibody

Item no.	ABC-ABO11603
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PSD-95, PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, SAP-90, SAP90
Available
Primary Accession	P78352
Application	WB, IHC-P
Clonality	Polyclonal
Gene ID	1742
Reactivity	H, M, Rat
Legend image 1	Anti-PSD95 antibody, ABO11603, IHC(P)IHC(P): Human Intestinal Cancer Tissue
Type image 1	IHC
Dilution image 1	0.5-1 µg/ml
Legend image 2	Anti-PSD95 antibody, ABO11603, IHC(P)IHC(P): Human Mammary Cancer Tissue
Type image 2	IHC
Dilution image 2	0.5-1 µg/ml
Legend image 3	Anti-PSD95 antibody, ABO11603, IHC(P)IHC(P): Human Placenta Tissue
Type image 3	IHC
Legend image 4	Anti-PSD95 antibody, ABO11603, All Western blottingAll lanes: Anti-DLG4 (ABO11603) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 80KDObserved bind size: 100KD
Type image 4	WB
Calculated MW	80495
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for Disks large homolog 4(DLG4) detection. Tested with WB, IHC-P in Human; Mouse; Rat.
Protein Function	Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity). .
Subcellular Localization	Cell membrane ; Peripheral membrane protein . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cell projection, axon . Cell junction, synapse . High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.
Tissue Specificity	Brain.
Protein Name	Disks large homolog 4
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human PSD95(492-507aa RRVERREWSRLKAKDW), identical to the related rat and mouse sequences.
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the MAGUK family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/4/2024

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